Negative cofitness for MMP_RS06975 from Methanococcus maripaludis S2

sulfide-dependent adenosine diphosphate thiazole synthase
SEED: Thiazole biosynthetic enzyme Thi4 / Ribose 1,5-bisphosphate or 5-ribose-1,2-cyclic phosphate dehydrogenase
KEGG: thiamine biosynthetic enzyme

Computing cofitness values with 700 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	MMP_RS03215		MBL fold metallo-hydrolase	-0.44
2	MMP_RS01370		acetate--CoA ligase family protein	-0.42
3	MMP_RS06575		fluoride efflux transporter CrcB	-0.31
4	MMP_RS04730		flavodoxin family protein	-0.27
5	MMP_RS03385		cation diffusion facilitator family transporter	-0.26
6	MMP_RS06570		DUF190 domain-containing protein	-0.24
7	MMP_RS01300		hypothetical protein	-0.24
8	MMP_RS08860		MinD/ParA family protein	-0.24
9	MMP_RS08075		DUF749 domain-containing protein	-0.23
10	MMP_RS07795		site-2 protease family protein	-0.23
11	MMP_RS01275		class III signal peptide-containing protein	-0.22
12	MMP_RS07115		MBL fold metallo-hydrolase	-0.22
13	MMP_RS03020		peptidylprolyl isomerase	-0.20
14	MMP_RS07350		preprotein translocase subunit Sec61beta	-0.20
15	MMP_RS08455		multiprotein bridging factor aMBF1	-0.20
16	MMP_RS01270		prepilin peptidase	-0.20
17	MMP_RS02880		AmmeMemoRadiSam system radical SAM enzyme	-0.20
18	MMP_RS08400		MJ0307 family thioredoxin	-0.19
19	MMP_RS01310		hypothetical protein	-0.19
20	MMP_RS07140		TIGR00341 family protein	-0.18

Or look for positive cofitness