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  • Negative cofitness for MMP_RS06540 from Methanococcus maripaludis S2

    3-methyl-2-oxobutanoate dehydrogenase subunit VorB
    SEED: Ketoisovalerate oxidoreductase subunit VorB (EC 1.2.7.7)
    KEGG: 2-oxoisovalerate ferredoxin oxidoreductase, alpha subunit

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS00310 CBS domain-containing protein -0.28
    2 MMP_RS04155 MFS transporter -0.27
    3 MMP_RS02940 TatD family hydrolase -0.26
    4 MMP_RS04355 ribonuclease H family protein -0.25
    5 MMP_RS09010 hypothetical protein -0.24
    6 MMP_RS03090 cation:proton antiporter -0.24
    7 MMP_RS04510 ABC transporter permease subunit -0.23
    8 MMP_RS05925 small nuclear ribonucleoprotein -0.23
    9 MMP_RS04475 nitrogen fixation -0.22
    10 MMP_RS00930 ABC transporter permease -0.22
    11 MMP_RS02975 DUF2124 domain-containing protein -0.22
    12 MMP_RS00915 DUF116 domain-containing protein -0.22
    13 MMP_RS07525 4Fe-4S binding protein -0.22
    14 MMP_RS07075 phosphomannomutase/phosphoglucomutase -0.21
    15 MMP_RS04450 P-II family nitrogen regulator -0.21
    16 MMP_RS04465 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE -0.21
    17 MMP_RS06485 zinc ribbon domain-containing protein -0.21
    18 MMP_RS04460 nitrogenase molybdenum-iron protein subunit beta -0.21
    19 MMP_RS03070 AzlD domain-containing protein -0.21
    20 MMP_RS05685 winged helix-turn-helix domain-containing protein -0.21

    Or look for positive cofitness