Negative cofitness for MMP_RS05265 from Methanococcus maripaludis S2

2-isopropylmalate synthase
SEED: (R)-citramalate synthase (EC 2.3.1.182)
KEGG: D-citramalate synthase

Computing cofitness values with 700 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	MMP_RS08665		hypothetical protein	-0.42
2	MMP_RS08250		pyruvate kinase	-0.40
3	MMP_RS08770		hypothetical protein	-0.38
4	MMP_RS08285		serine/threonine protein kinase	-0.38
5	MMP_RS01280		DUF515 domain-containing protein	-0.37
6	MMP_RS01290		class III signal peptide-containing protein	-0.37
7	MMP_RS01310		hypothetical protein	-0.37
8	MMP_RS00240		type II secretion system F family protein	-0.36
9	MMP_RS00245		type II secretion system F family protein	-0.36
10	MMP_RS01305		hypothetical protein	-0.35
11	MMP_RS01285		hypothetical protein	-0.35
12	MMP_RS08490		hypothetical protein	-0.34
13	MMP_RS01275		class III signal peptide-containing protein	-0.34
14	MMP_RS01315		DUF2341 domain-containing protein	-0.34
15	MMP_RS01295		hypothetical protein	-0.33
16	MMP_RS08290		DNA-binding protein Alba	-0.33
17	MMP_RS08675		class III signal peptide-containing protein	-0.32
18	MMP_RS00250		Flp pilus assembly complex ATPase component TadA	-0.32
19	MMP_RS08245		DUF4013 domain-containing protein	-0.32
20	MMP_RS07855		class I SAM-dependent methyltransferase	-0.31

Or look for positive cofitness