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  • Negative cofitness for MMP_RS05105 from Methanococcus maripaludis S2

    thymidylate synthase
    SEED: Thymidylate synthase (EC 2.1.1.45)
    KEGG: thymidylate synthase

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS01370 acetate--CoA ligase family protein -0.31
    2 MMP_RS03215 MBL fold metallo-hydrolase -0.31
    3 MMP_RS02405 hypothetical protein -0.29
    4 MMP_RS04665 SBBP repeat-containing protein -0.29
    5 MMP_RS03620 hypothetical protein -0.27
    6 MMP_RS04550 S-layer protein -0.26
    7 MMP_RS06075 class I SAM-dependent methyltransferase -0.25
    8 MMP_RS03615 4Fe-4S binding protein -0.24
    9 MMP_RS00760 branched-chain-amino-acid transaminase -0.22
    10 MMP_RS06545 ferredoxin family protein -0.22
    11 MMP_RS05620 radical SAM protein -0.21
    12 MMP_RS05695 phospholipase D-like domain-containing protein -0.20
    13 MMP_RS05435 5'/3'-nucleotidase SurE -0.19
    14 MMP_RS05600 AglZ/HisF2 family acetamidino modification protein -0.19
    15 MMP_RS04825 protein-glutamate O-methyltransferase CheR -0.19
    16 MMP_RS06765 flap endonuclease-1 -0.19
    17 MMP_RS05560 deoxyuridine 5'-triphosphate nucleotidohydrolase -0.19
    18 MMP_RS03150 phosphoglycerate mutase -0.19
    19 MMP_RS07560 prefoldin subunit alpha -0.18
    20 MMP_RS04120 hypothetical protein -0.18

    Or look for positive cofitness