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  • Negative cofitness for MMP_RS03350 from Methanococcus maripaludis S2

    winged helix-turn-helix domain-containing protein
    SEED: Transcriptional regulator, ArsR family member

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS05780 multidrug resistance efflux transporter family protein -0.34
    2 MMP_RS04320 uroporphyrinogen decarboxylase family protein -0.32
    3 MMP_RS01055 hypothetical protein -0.31
    4 MMP_RS00430 hypothetical protein -0.31
    5 MMP_RS03220 RNA 2' 3'-cyclic phosphodiesterase -0.27
    6 MMP_RS01845 hypothetical protein -0.27
    7 MMP_RS06075 class I SAM-dependent methyltransferase -0.26
    8 MMP_RS07840 ribonuclease III -0.26
    9 MMP_RS08430 HAD family hydrolase -0.26
    10 MMP_RS01855 2-hydroxyacyl-CoA dehydratase family protein -0.26
    11 MMP_RS06990 CatB-related O-acetyltransferase -0.26
    12 MMP_RS02045 tRNA-Met -0.26
    13 MMP_RS00975 HD domain-containing protein -0.25
    14 MMP_RS04885 sulfite exporter TauE/SafE family protein -0.25
    15 MMP_RS03430 bile acid:sodium symporter family protein -0.24
    16 MMP_RS06225 DNA double-strand break repair nuclease NurA -0.24
    17 MMP_RS06720 response regulator transcription factor -0.24
    18 MMP_RS02300 NAD(P)H-dependent oxidoreductase -0.24
    19 MMP_RS02390 NifB/NifX family molybdenum-iron cluster-binding protein -0.24
    20 MMP_RS06715 cache domain-containing protein -0.23

    Or look for positive cofitness