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  • Negative cofitness for MMP_RS02615 from Methanococcus maripaludis S2

    cobaltochelatase subunit CobN
    SEED: CobN component of cobalt chelatase involved in B12 biosynthesis
    KEGG: cobaltochelatase CobN

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS07195 M20 family metallo-hydrolase -0.36
    2 MMP_RS08100 8-amino-7-oxononanoate synthase -0.33
    3 MMP_RS07645 aldehyde dehydrogenase family protein -0.32
    4 MMP_RS02280 DUF211 domain-containing protein -0.31
    5 MMP_RS08345 4Fe-4S binding protein -0.31
    6 MMP_RS04500 adenosylmethionine--8-amino-7-oxononanoate transaminase -0.30
    7 MMP_RS02135 DUF5612 domain-containing protein -0.30
    8 MMP_RS08105 6-carboxyhexanoate--CoA ligase -0.30
    9 MMP_RS06215 30S ribosomal protein S6e -0.30
    10 MMP_RS01415 DUF2067 domain-containing protein -0.30
    11 MMP_RS06370 biotin synthase BioB -0.30
    12 MMP_RS08095 dethiobiotin synthase -0.29
    13 MMP_RS03155 precorrin-6A reductase -0.29
    14 MMP_RS03130 hypothetical protein -0.29
    15 MMP_RS00050 AarF/UbiB family protein -0.29
    16 MMP_RS03715 class III signal peptide-containing protein -0.29
    17 MMP_RS08340 4Fe-4S binding protein -0.28
    18 MMP_RS08445 DUF2099 family protein -0.28
    19 MMP_RS01060 calcium/sodium antiporter -0.27
    20 MMP_RS05800 B12-binding domain-containing radical SAM protein -0.27

    Or look for positive cofitness