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  • Negative cofitness for MMP_RS01635 from Methanococcus maripaludis S2

    thiamine pyrophosphate-dependent enzyme
    SEED: 2-oxoglutarate oxidoreductase, beta subunit (EC 1.2.7.3)
    KEGG: 2-oxoglutarate ferredoxin oxidoreductase subunit beta

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS05640 UTP--glucose-1-phosphate uridylyltransferase GalU -0.45
    2 MMP_RS06670 glucose-6-phosphate isomerase -0.44
    3 MMP_RS07075 phosphomannomutase/phosphoglucomutase -0.44
    4 MMP_RS01725 class I SAM-dependent methyltransferase family protein -0.44
    5 MMP_RS01900 hypothetical protein -0.42
    6 MMP_RS01875 N-acetyltransferase -0.42
    7 MMP_RS01890 nucleotide sugar dehydrogenase -0.41
    8 MMP_RS01905 glycosyltransferase -0.41
    9 MMP_RS01885 Gfo/Idh/MocA family oxidoreductase -0.41
    10 MMP_RS04720 DedA family protein -0.40
    11 MMP_RS01880 DegT/DnrJ/EryC1/StrS family aminotransferase -0.40
    12 MMP_RS01925 DUF1616 domain-containing protein -0.40
    13 MMP_RS02015 amidohydrolase -0.40
    14 MMP_RS01895 flippase -0.39
    15 MMP_RS08660 DHH family phosphoesterase -0.39
    16 MMP_RS08440 cell division protein SepF -0.39
    17 MMP_RS00040 TIGR03576 family pyridoxal phosphate-dependent enzyme -0.39
    18 MMP_RS06940 polyprenyl diphosphate synthase -0.38
    19 MMP_RS02145 winged helix-turn-helix transcriptional regulator -0.38
    20 MMP_RS01960 hypothetical protein -0.38

    Or look for positive cofitness