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  • Negative cofitness for MMP_RS01450 from Methanococcus maripaludis S2

    tRNA pseudouridine(38-40) synthase TruA
    SEED: tRNA pseudouridine synthase A (EC 4.2.1.70)
    KEGG: tRNA pseudouridine synthase A

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS00150 AAA family ATPase -0.31
    2 MMP_RS06900 coenzyme F420-reducing hydrogenase FrhD protein -0.31
    3 MMP_RS03215 MBL fold metallo-hydrolase -0.30
    4 MMP_RS05535 hypothetical protein -0.29
    5 MMP_RS00915 DUF116 domain-containing protein -0.28
    6 MMP_RS06275 ATP-dependent DNA helicase -0.28
    7 MMP_RS04955 DNA topoisomerase I -0.27
    8 MMP_RS06395 ThiF family adenylyltransferase -0.26
    9 MMP_RS01370 acetate--CoA ligase family protein -0.26
    10 MMP_RS07695 DUF3236 domain-containing protein -0.26
    11 MMP_RS03245 DNA repair and recombination protein RadB -0.26
    12 MMP_RS04625 DEAD/DEAH box helicase -0.25
    13 MMP_RS05160 cupredoxin family copper-binding protein -0.25
    14 MMP_RS07125 coenzyme F420-reducing hydrogenase FrhD protein -0.25
    15 MMP_RS08660 DHH family phosphoesterase -0.24
    16 MMP_RS00520 RNA polymerase Rpb4 family protein -0.24
    17 MMP_RS08620 flagellar accessory protein FlaH -0.23
    18 MMP_RS03560 Na+/H+ antiporter NhaC family protein -0.23
    19 MMP_RS04250 PC4/YdbC family ssDNA-binding protein -0.23
    20 MMP_RS06435 CBS domain-containing protein -0.22

    Or look for positive cofitness