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  • Negative cofitness for MMP_RS00750 from Methanococcus maripaludis S2

    fumarate hydratase
    SEED: Fumarate hydratase class I, aerobic (EC 4.2.1.2); L(+)-tartrate dehydratase alpha subunit (EC 4.2.1.32)
    KEGG: fumarate hydratase subunit alpha

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS08285 serine/threonine protein kinase -0.50
    2 MMP_RS08130 IGHMBP2 family helicase -0.47
    3 MMP_RS09065 hypothetical protein -0.47
    4 MMP_RS08640 TIM barrel protein -0.45
    5 MMP_RS08665 hypothetical protein -0.44
    6 MMP_RS08290 DNA-binding protein Alba -0.43
    7 MMP_RS05865 hypothetical protein -0.43
    8 MMP_RS07775 alanine dehydrogenase -0.42
    9 MMP_RS07550 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha -0.42
    10 MMP_RS02025 DNA-directed DNA polymerase -0.42
    11 MMP_RS08080 YchF/TatD family DNA exonuclease -0.41
    12 MMP_RS08205 stage II sporulation protein M -0.40
    13 MMP_RS06910 RlmF-related methyltransferase -0.40
    14 MMP_RS07985 nitroreductase family protein -0.40
    15 MMP_RS08770 hypothetical protein -0.38
    16 MMP_RS07840 ribonuclease III -0.38
    17 MMP_RS08200 archaeosine synthase subunit alpha -0.38
    18 MMP_RS06070 iron ABC transporter substrate-binding protein -0.37
    19 MMP_RS08980 hypothetical protein -0.37
    20 MMP_RS04060 hypothetical protein -0.37

    Or look for positive cofitness