Negative cofitness for MMP_RS00730 from Methanococcus maripaludis S2

5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
SEED: Biotin synthase-related protein in some methanogens
KEGG: biotin synthetase

Computing cofitness values with 700 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	MMP_RS04190		hypothetical protein	-0.48
2	MMP_RS06345		formate dehydrogenase accessory sulfurtransferase FdhD	-0.46
3	MMP_RS00990		hypothetical protein	-0.45
4	MMP_RS06700		hypothetical protein	-0.44
5	MMP_RS06715		cache domain-containing protein	-0.44
6	MMP_RS06720		response regulator transcription factor	-0.44
7	MMP_RS01320		hypothetical protein	-0.44
8	MMP_RS08410		DUF169 domain-containing protein	-0.43
9	MMP_RS01855		2-hydroxyacyl-CoA dehydratase family protein	-0.43
10	MMP_RS01985		F420-dependent methylenetetrahydromethanopterin dehydrogenase	-0.43
11	MMP_RS06680		Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain	-0.43
12	MMP_RS01135		molybdate ABC transporter substrate-binding protein	-0.43
13	MMP_RS06305		transporter substrate-binding domain-containing protein	-0.42
14	MMP_RS02375		hypothetical protein	-0.42
15	MMP_RS08485		tungstate ABC transporter substrate-binding protein WtpA	-0.42
16	MMP_RS06910		RlmF-related methyltransferase	-0.41
17	MMP_RS09060		hypothetical protein	-0.41
18	MMP_RS07985		nitroreductase family protein	-0.40
19	MMP_RS08390		DUF5400 domain-containing protein	-0.40
20	MMP_RS08380		phosphatase PAP2 family protein	-0.39

Or look for positive cofitness