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  • Negative cofitness for MMP_RS00695 from Methanococcus maripaludis S2

    biotin--[acetyl-CoA-carboxylase] ligase
    SEED: Biotin-protein ligase (EC 6.3.4.15)
    KEGG: BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase

    Computing cofitness values with 700 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 MMP_RS08480 molybdate ABC transporter substrate-binding protein -0.34
    2 MMP_RS08640 TIM barrel protein -0.33
    3 MMP_RS08250 pyruvate kinase -0.31
    4 MMP_RS08080 YchF/TatD family DNA exonuclease -0.31
    5 MMP_RS08850 hypothetical protein -0.30
    6 MMP_RS08405 MFS transporter -0.30
    7 MMP_RS08490 hypothetical protein -0.30
    8 MMP_RS07985 nitroreductase family protein -0.30
    9 MMP_RS08700 hypothetical protein -0.29
    10 MMP_RS09060 hypothetical protein -0.29
    11 MMP_RS08325 hypothetical protein -0.28
    12 MMP_RS09065 hypothetical protein -0.28
    13 MMP_RS07590 hypothetical protein -0.27
    14 MMP_RS08285 serine/threonine protein kinase -0.27
    15 MMP_RS08390 DUF5400 domain-containing protein -0.27
    16 MMP_RS06655 glycoside hydrolase family 15 protein -0.26
    17 MMP_RS07650 TldD/PmbA family protein -0.26
    18 MMP_RS06335 HAD family hydrolase -0.26
    19 MMP_RS08205 stage II sporulation protein M -0.26
    20 MMP_RS08130 IGHMBP2 family helicase -0.25

    Or look for positive cofitness