Negative cofitness for MMP_RS00235 from Methanococcus maripaludis S2

HDIG domain-containing protein
SEED: metal-dependent phosphohydrolase
KEGG: uncharacterized protein

Computing cofitness values with 700 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	MMP_RS07850		prephenate dehydratase	-0.40
2	MMP_RS06725		hypothetical protein	-0.38
3	MMP_RS03560		Na+/H+ antiporter NhaC family protein	-0.36
4	MMP_RS07410		4-demethylwyosine synthase TYW1	-0.35
5	MMP_RS07115		MBL fold metallo-hydrolase	-0.35
6	MMP_RS02960		class I SAM-dependent methyltransferase family protein	-0.34
7	MMP_RS07700		DUF1188 domain-containing protein	-0.34
8	MMP_RS00735		5 10-methenyltetrahydromethanopterin hydrogenase	-0.33
9	MMP_RS07695		DUF3236 domain-containing protein	-0.32
10	MMP_RS00730		5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB	-0.31
11	MMP_RS00315		Nif3-like dinuclear metal center hexameric protein	-0.31
12	MMP_RS04850		UPF0254 family protein	-0.30
13	MMP_RS06395		ThiF family adenylyltransferase	-0.29
14	MMP_RS06435		CBS domain-containing protein	-0.29
15	MMP_RS00725		5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC	-0.29
16	MMP_RS04785		hypothetical protein	-0.27
17	MMP_RS03790		hypothetical protein	-0.27
18	MMP_RS07835		TldD/PmbA family protein	-0.27
19	MMP_RS07650		TldD/PmbA family protein	-0.25
20	MMP_RS07355		transcription factor S	-0.24

Or look for positive cofitness