Negative cofitness for H281DRAFT_00385 from Paraburkholderia bryophila 376MFSha3.1

2-isopropylmalate synthase
SEED: 2-isopropylmalate synthase (EC 2.3.3.13)
KEGG: 2-isopropylmalate synthase

Computing cofitness values with 128 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 H281DRAFT_03046 6-phosphogluconate dehydrogenase (decarboxylating) -0.38
2 H281DRAFT_04257 D-tyrosyl-tRNA(Tyr) deacylase -0.31
3 H281DRAFT_00046 Predicted periplasmic or secreted lipoprotein -0.31
4 H281DRAFT_04604 Protein of unknown function (DUF2863) -0.31
5 H281DRAFT_02054 penicillin-binding protein 6. Serine peptidase. MEROPS family S11 -0.30
6 H281DRAFT_03951 hypothetical protein -0.30
7 H281DRAFT_02150 phosphoheptose isomerase -0.30
8 H281DRAFT_04749 aspartate 4-decarboxylase -0.27
9 H281DRAFT_01932 hypothetical protein -0.27
10 H281DRAFT_05392 hypothetical protein -0.27
11 H281DRAFT_04840 Uncharacterized protein conserved in bacteria -0.26
12 H281DRAFT_00074 UDP-galactose 4-epimerase -0.26
13 H281DRAFT_05300 amino acid ABC transporter substrate-binding protein, PAAT family -0.26
14 H281DRAFT_06069 tRNA pseudouridine38-40 synthase -0.26
15 H281DRAFT_03703 NADP-dependent 3-hydroxy acid dehydrogenase YdfG -0.26
16 H281DRAFT_05816 soluble lytic murein transglycosylase -0.26
17 H281DRAFT_02146 Integrase -0.25
18 H281DRAFT_03548 H+/gluconate symporter -0.25
19 H281DRAFT_05802 dipeptide transport system substrate-binding protein -0.25
20 H281DRAFT_03918 hypothetical protein -0.25

Or look for positive cofitness