Negative cofitness for Ga0059261_3612 from Sphingomonas koreensis DSMZ 15582

Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
SEED: FolM Alternative dihydrofolate reductase 1

Computing cofitness values with 166 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Ga0059261_0361		conserved hypothetical protein, YceG family	-0.48
2	Ga0059261_1819		S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	-0.41
3	Ga0059261_2013		signal peptidase I, bacterial type	-0.38
4	Ga0059261_0880		Tetratricopeptide repeat	-0.38
5	Ga0059261_1544		transcriptional regulator, TetR family	-0.38
6	Ga0059261_0065		ABC-type dipeptide transport system, periplasmic component	-0.38
7	Ga0059261_3645		Transmembrane secretion effector	-0.37
8	Ga0059261_1541		Predicted esterase of the alpha/beta hydrolase fold	-0.37
9	Ga0059261_2355		Ogr/Delta-like zinc finger	-0.36
10	Ga0059261_0140		tRNA-U20-dihydrouridine synthase	-0.36
11	Ga0059261_1820		Lactoylglutathione lyase and related lyases	-0.35
12	Ga0059261_1821		formyltetrahydrofolate deformylase (EC 3.5.1.10)	-0.35
13	Ga0059261_2203		hypothetical protein	-0.34
14	Ga0059261_3969		Serine hydrolase	-0.34
15	Ga0059261_0267		Predicted membrane protein	-0.34
16	Ga0059261_1676		transcriptional regulator, IclR family	-0.33
17	Ga0059261_2513		Domain of unknown function (DUF4115)/Helix-turn-helix domain	-0.32
18	Ga0059261_2191		ribosomal subunit interface protein	-0.32
19	Ga0059261_2354		Toprim-like	-0.32
20	Ga0059261_2202		hypothetical protein	-0.31

Or look for positive cofitness