Negative cofitness for Psest_0725 from Pseudomonas stutzeri RCH2

Negative regulator of beta-lactamase expression
SEED: N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD
KEGG: AmpD protein

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_3647		Indole-3-glycerol phosphate synthase	-0.37
2	Psest_3649		glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	-0.35
3	Psest_0062		tryptophan synthase, alpha subunit	-0.34
4	Psest_3648		anthranilate phosphoribosyltransferase	-0.33
5	Psest_2584		Phosphoribosylanthranilate isomerase	-0.33
6	Psest_0063		tryptophan synthase, beta subunit	-0.31
7	Psest_3650		anthranilate synthase component I, non-proteobacterial lineages	-0.31
8	Psest_3384		glutamate 5-kinase	-0.31
9	Psest_0508		gamma-glutamyl phosphate reductase	-0.30
10	Psest_2329		Transcriptional regulator	-0.30
11	Psest_1473		phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent	-0.29
12	Psest_0313		5,10-methylenetetrahydrofolate reductase, prokaryotic form	-0.29
13	Psest_3998		glutamate--cysteine ligase	-0.27
14	Psest_3818		endoribonuclease L-PSP, putative	-0.27
15	Psest_0494		Rhodanese-related sulfurtransferase	-0.27
16	Psest_0153		imidazole glycerol phosphate synthase, glutamine amidotransferase subunit	-0.27
17	Psest_2484		Molecular chaperone, HSP90 family	-0.26
18	Psest_3297		histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data)	-0.26
19	Psest_3731		exopolyphosphatase	-0.26
20	Psest_3990		PAP2 superfamily.	-0.26

Or look for positive cofitness