Negative cofitness for Psest_0608 from Pseudomonas stutzeri RCH2

Cd(II)/Pb(II)-responsive transcriptional regulator
SEED: Transcriptional regulator, MerR family

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_3444		Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs	-0.48
2	Psest_0786		tripartite ATP-independent periplasmic transporter solute receptor, DctP family	-0.47
3	Psest_3472		Long-chain acyl-CoA synthetases (AMP-forming)	-0.46
4	Psest_0358		Neutral trehalase	-0.45
5	Psest_3976		PAS domain S-box	-0.42
6	Psest_2753		Uncharacterized protein conserved in bacteria	-0.42
7	Psest_0373		L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-0.41
8	Psest_0539		Acyl-CoA dehydrogenases	-0.40
9	Psest_0770		alkylphosphonate utilization operon protein PhnA	-0.38
10	Psest_3886		Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	-0.38
11	Psest_0552		conserved hypothetical protein, proteobacterial	-0.37
12	Psest_0788		Uncharacterized conserved protein	-0.37
13	Psest_1634		tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain	-0.37
14	Psest_1468		hypothetical protein	-0.37
15	Psest_0847		drug resistance transporter, EmrB/QacA subfamily	-0.36
16	Psest_0728		hydrolase, TatD family	-0.36
17	Psest_2998		Glutathione peroxidase	-0.36
18	Psest_3043		periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family	-0.36
19	Psest_2763		Cellobiose phosphorylase	-0.36
20	Psest_0034		Outer membrane receptor proteins, mostly Fe transport	-0.36

Or look for positive cofitness