Negative cofitness for Psest_3901 from Pseudomonas stutzeri RCH2

diguanylate cyclase (GGDEF) domain
SEED: diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_0445		PAS domain S-box/diguanylate cyclase (GGDEF) domain	-0.56
2	Psest_4097		PAS domain S-box/diguanylate cyclase (GGDEF) domain	-0.53
3	Psest_0262		PAS domain S-box	-0.52
4	Psest_3981		hypothetical protein	-0.45
5	Psest_0248		Transcriptional regulator	-0.43
6	Psest_0465		Acetyltransferase (isoleucine patch superfamily)	-0.42
7	Psest_0804		hypothetical protein	-0.42
8	Psest_4175		Flagellar motor switch/type III secretory pathway protein	-0.41
9	Psest_4391		ATPases involved in chromosome partitioning	-0.41
10	Psest_0140		choline/carnitine/betaine transport	-0.39
11	Psest_1163		diguanylate cyclase (GGDEF) domain	-0.39
12	Psest_0342		ABC-type amino acid transport/signal transduction systems, periplasmic component/domain	-0.39
13	Psest_4017		hypothetical protein	-0.38
14	Psest_1334		Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II	-0.38
15	Psest_4383		Site-specific recombinases, DNA invertase Pin homologs	-0.38
16	Psest_0873		HipA N-terminal domain	-0.38
17	Psest_4297		PAS domain S-box	-0.37
18	Psest_0250		Glycosyltransferases, probably involved in cell wall biogenesis	-0.37
19	Psest_0297		Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-0.36
20	Psest_4018		hypothetical protein	-0.36

Or look for positive cofitness