Negative cofitness for Psest_3745 from Pseudomonas stutzeri RCH2

Uncharacterized enzyme of heme biosynthesis
SEED: Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)
KEGG: HemY protein

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_2673		Arabinose efflux permease	-0.36
2	Psest_2102		5-methyltetrahydrofolate--homocysteine methyltransferase	-0.32
3	Psest_0771		Acyl-CoA hydrolase	-0.30
4	Psest_3116		electron transport complex, RnfABCDGE type, G subunit	-0.29
5	Psest_3649		glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	-0.28
6	Psest_2484		Molecular chaperone, HSP90 family	-0.28
7	Psest_3647		Indole-3-glycerol phosphate synthase	-0.28
8	Psest_0063		tryptophan synthase, beta subunit	-0.27
9	Psest_3650		anthranilate synthase component I, non-proteobacterial lineages	-0.27
10	Psest_3648		anthranilate phosphoribosyltransferase	-0.27
11	Psest_1310		ABC-type branched-chain amino acid transport system, permease component	-0.26
12	Psest_0062		tryptophan synthase, alpha subunit	-0.26
13	Psest_2083		Putative sterol carrier protein	-0.26
14	Psest_2584		Phosphoribosylanthranilate isomerase	-0.26
15	Psest_0153		imidazole glycerol phosphate synthase, glutamine amidotransferase subunit	-0.25
16	Psest_3943		Phosphoribosyl-AMP cyclohydrolase	-0.25
17	Psest_2845		[Protein-PII] uridylyltransferase	-0.25
18	Psest_1140		2-dehydropantoate 2-reductase	-0.25
19	Psest_1295		Aspartate/tyrosine/aromatic aminotransferase	-0.24
20	Psest_2672		Predicted membrane protein	-0.24

Or look for positive cofitness