Negative cofitness for Psest_3079 from Pseudomonas stutzeri RCH2

L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data)
Original annotation: delta-1-pyrroline-5-carboxylate dehydrogenase (PutA C-terminal domain)
SEED: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
KEGG: proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_3384		glutamate 5-kinase	-0.25
2	Psest_0508		gamma-glutamyl phosphate reductase	-0.24
3	Psest_1075		Predicted transcriptional regulators	-0.21
4	Psest_2988		aspartate kinase, monofunctional class	-0.18
5	Psest_1080		Acetyl/propionyl-CoA carboxylase, alpha subunit	-0.17
6	Psest_1083		3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data)	-0.17
7	Psest_0348		hypothetical protein	-0.16
8	Psest_0218		Acyl-CoA hydrolase	-0.16
9	Psest_2864		Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-0.16
10	Psest_0955		D,L-lactate:H+ symporter (from data)	-0.15
11	Psest_1527		Na+/proline symporter	-0.15
12	Psest_0359		Transcriptional regulators	-0.15
13	Psest_0312		Superfamily II DNA and RNA helicases	-0.15
14	Psest_4193		Predicted signal transduction protein	-0.15
15	Psest_4084		oxaloacetate decarboxylase alpha subunit	-0.15
16	Psest_0782		Transcriptional regulator of aromatic amino acids metabolism	-0.15
17	Psest_1479		NAD(P)H:quinone oxidoreductase, type IV	-0.15
18	Psest_1664		Glycerophosphoryl diester phosphodiesterase	-0.15
19	Psest_2331		phospho-2-dehydro-3-deoxyheptonate aldolase	-0.15
20	Psest_3143		Uncharacterized protein conserved in bacteria	-0.15

Or look for positive cofitness