Negative cofitness for Psest_0298 from Pseudomonas stutzeri RCH2

Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
SEED: twitching motility protein PilH
KEGG: twitching motility two-component system response regulator PilH

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_1535		FKBP-type peptidyl-prolyl cis-trans isomerases 1	-0.26
2	Psest_3770		secondary thiamine-phosphate synthase enzyme	-0.25
3	Psest_0056		Glutathione S-transferase	-0.24
4	Psest_2441		hypothetical protein	-0.24
5	Psest_2060		PQQ-dependent dehydrogenase, methanol/ethanol family	-0.23
6	Psest_1991		Glutathione S-transferase	-0.23
7	Psest_3862		phosphoenolpyruvate-protein phosphotransferase	-0.22
8	Psest_3468		hypothetical protein	-0.22
9	Psest_0449		Glutamine synthetase adenylyltransferase	-0.22
10	Psest_0236		Predicted SAM-dependent methyltransferases	-0.21
11	Psest_1823		Nucleoside-diphosphate-sugar epimerases	-0.21
12	Psest_4075		symporter for L-glutamate, L-glutamine, and L-proline (from data)	-0.21
13	Psest_3768		haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-0.21
14	Psest_1537		Bacterioferritin-associated ferredoxin	-0.21
15	Psest_3693		Glycosyltransferases involved in cell wall biogenesis	-0.20
16	Psest_3162		amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family	-0.20
17	Psest_2042		PQQ-dependent catabolism-associated beta-propeller protein	-0.20
18	Psest_0771		Acyl-CoA hydrolase	-0.20
19	Psest_3214		phosphate acetyltransferase	-0.20
20	Psest_0720		Predicted hydrolase of the alpha/beta superfamily	-0.19

Or look for positive cofitness