Negative cofitness for Psest_0263 from Pseudomonas stutzeri RCH2

PAS domain S-box/diguanylate cyclase (GGDEF) domain
SEED: diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_3472		Long-chain acyl-CoA synthetases (AMP-forming)	-0.37
2	Psest_3444		Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs	-0.34
3	Psest_0788		Uncharacterized conserved protein	-0.34
4	Psest_3318		Predicted Zn-dependent proteases and their inactivated homologs	-0.34
5	Psest_0373		L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-0.34
6	Psest_2359		Predicted permeases	-0.33
7	Psest_3695		Histidine ammonia-lyase	-0.33
8	Psest_2763		Cellobiose phosphorylase	-0.33
9	Psest_0786		tripartite ATP-independent periplasmic transporter solute receptor, DctP family	-0.31
10	Psest_2753		Uncharacterized protein conserved in bacteria	-0.31
11	Psest_2666		Predicted acyl-CoA transferases/carnitine dehydratase	-0.31
12	Psest_0728		hydrolase, TatD family	-0.31
13	Psest_0056		Glutathione S-transferase	-0.30
14	Psest_1634		tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain	-0.30
15	Psest_0039		phosphoglucomutase, alpha-D-glucose phosphate-specific	-0.30
16	Psest_0539		Acyl-CoA dehydrogenases	-0.30
17	Psest_2928		Subtilisin-like serine proteases	-0.30
18	Psest_3347		TonB-dependent siderophore receptor	-0.30
19	Psest_3976		PAS domain S-box	-0.29
20	Psest_4150		fagellar hook-basal body proteins	-0.29

Or look for positive cofitness