Negative cofitness for Psest_2590 from Pseudomonas stutzeri RCH2

3-isopropylmalate dehydratase, small subunit
SEED: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
KEGG: 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_0310		The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family	-0.42
2	Psest_0487		Uncharacterized protein conserved in bacteria	-0.35
3	Psest_0515		rare lipoprotein A	-0.34
4	Psest_2555		hypothetical protein	-0.34
5	Psest_0311		efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-0.34
6	Psest_0309		RND family efflux transporter, MFP subunit	-0.33
7	Psest_4140		Acyl-CoA dehydrogenases	-0.30
8	Psest_1532		DNA recombination-dependent growth factor C	-0.30
9	Psest_0835		Collagenase and related proteases	-0.30
10	Psest_2136		Predicted homoserine dehydrogenase	-0.30
11	Psest_4078		L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	-0.29
12	Psest_1455		diguanylate cyclase (GGDEF) domain	-0.29
13	Psest_0514		lytic murein transglycosylase B	-0.29
14	Psest_2234		oxygen-independent coproporphyrinogen III oxidase	-0.29
15	Psest_2489		branched-chain amino acid uptake carrier	-0.28
16	Psest_2304		Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	-0.28
17	Psest_1995		protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific	-0.28
18	Psest_3938		Uncharacterized protein conserved in bacteria	-0.28
19	Psest_1625		hypothetical protein	-0.27
20	Psest_3416		Predicted ATPase (AAA+ superfamily)	-0.27

Or look for positive cofitness