Negative cofitness for Psest_2282 from Pseudomonas stutzeri RCH2

Dihydroorotate dehydrogenase
SEED: Phosphoserine aminotransferase (EC 2.6.1.52)

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_0536		thiamine-phosphate pyrophosphorylase	-0.29
2	Psest_1597		Protein of unknown function (DUF2933).	-0.27
3	Psest_3520		Short chain fatty acids transporter	-0.26
4	Psest_2889		Predicted flavoprotein involved in K+ transport	-0.26
5	Psest_2149		Ku protein, prokaryotic	-0.25
6	Psest_1511		Predicted redox protein, regulator of disulfide bond formation	-0.24
7	Psest_3003		Transcriptional regulator	-0.23
8	Psest_2891		TonB-dependent siderophore receptor	-0.23
9	Psest_3492		hypothetical protein	-0.23
10	Psest_2416		3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	-0.23
11	Psest_2659		Transcriptional regulator	-0.23
12	Psest_1357		Uncharacterized protein conserved in bacteria	-0.23
13	Psest_2225		Diacylglycerol kinase	-0.23
14	Psest_0733		Cation/multidrug efflux pump	-0.22
15	Psest_1071		Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-0.22
16	Psest_3522		3-hydroxybutyrate dehydrogenase	-0.22
17	Psest_2222		ribose-phosphate pyrophosphokinase	-0.22
18	Psest_1424		Lipoate-protein ligase A	-0.22
19	Psest_2914		membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family	-0.22
20	Psest_2657		acetate--CoA ligase	-0.21

Or look for positive cofitness