Negative cofitness for Psest_2223 from Pseudomonas stutzeri RCH2

cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
SEED: transcriptional regulator, Crp/Fnr family

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_3983		Aldo/keto reductases, related to diketogulonate reductase	-0.25
2	Psest_2080		hypothetical protein	-0.23
3	Psest_0354		Malate synthase G (EC 2.3.3.9) (from data)	-0.23
4	Psest_2475		Acyl-CoA dehydrogenases	-0.22
5	Psest_2014		Isocitrate lyase (EC 4.1.3.1) (from data)	-0.21
6	Psest_1000		PAS domain S-box	-0.21
7	Psest_0701		uncharacterized radical SAM protein YgiQ	-0.20
8	Psest_4012		TRAP-type mannitol/chloroaromatic compound transport system, small permease component	-0.20
9	Psest_1716		Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-0.20
10	Psest_1087		uncharacterized peroxidase-related enzyme	-0.20
11	Psest_2811		Uncharacterized conserved protein	-0.19
12	Psest_3393		hypothetical protein	-0.19
13	Psest_3438		Glutamate dehydrogenase/leucine dehydrogenase	-0.19
14	Psest_2567		PEP phosphonomutase and related enzymes	-0.19
15	Psest_1037		acetolactate synthase, small subunit	-0.18
16	Psest_1697		Gamma-aminobutyrate permease and related permeases	-0.18
17	Psest_0419		Acyl-CoA dehydrogenase (EC 1.3.8.7) (from data)	-0.18
18	Psest_0262		PAS domain S-box	-0.18
19	Psest_0999		Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-0.18
20	Psest_3035		Protein of unknown function (DUF1282).	-0.18

Or look for positive cofitness