Negative cofitness for Psest_2136 from Pseudomonas stutzeri RCH2

Predicted homoserine dehydrogenase
SEED: Homoserine dehydrogenase (EC 1.1.1.3)

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_1006		dTDP-4-dehydrorhamnose reductase	-0.61
2	Psest_3161		amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family	-0.38
3	Psest_3932		nitrogen regulation protein NR(I)	-0.38
4	Psest_1882		Signal transduction histidine kinase	-0.37
5	Psest_4005		Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB	-0.37
6	Psest_3162		amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family	-0.36
7	Psest_4297		PAS domain S-box	-0.36
8	Psest_2027		ATP-dependent Clp protease ATP-binding subunit clpA	-0.36
9	Psest_0327		Transcriptional regulator	-0.35
10	Psest_3419		Predicted transcriptional regulators	-0.35
11	Psest_0736		Methyl-accepting chemotaxis protein	-0.35
12	Psest_1881		Nitroreductase	-0.35
13	Psest_3993		alpha-L-glutamate ligases, RimK family	-0.35
14	Psest_0559		Sortase and related acyltransferases	-0.34
15	Psest_0313		5,10-methylenetetrahydrofolate reductase, prokaryotic form	-0.34
16	Psest_1188		FOG: EAL domain	-0.33
17	Psest_2591		3-isopropylmalate dehydratase, large subunit	-0.33
18	Psest_3943		Phosphoribosyl-AMP cyclohydrolase	-0.33
19	Psest_1311		Branched-chain amino acid ABC-type transport system, permease components	-0.33
20	Psest_3298		histidinol dehydrogenase	-0.33

Or look for positive cofitness