Negative cofitness for Psest_2047 from Pseudomonas stutzeri RCH2

Signal transduction histidine kinase
SEED: Nitrate/nitrite sensor protein (EC 2.7.3.-)
KEGG: two-component system, NarL family, sensor histidine kinase UhpB

Computing cofitness values with 424 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psest_2486		Uncharacterized protein, possibly involved in aromatic compounds catabolism	-0.25
2	Psest_3282		Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)	-0.24
3	Psest_1415		Restriction endonuclease	-0.24
4	Psest_2600		Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-0.24
5	Psest_2072		Methyltransferase domain.	-0.23
6	Psest_1212		Isopenicillin N synthase and related dioxygenases	-0.22
7	Psest_0588		Short-chain dehydrogenases of various substrate specificities	-0.22
8	Psest_2233		Methyl-accepting chemotaxis protein	-0.21
9	Psest_2860		hypothetical protein	-0.21
10	Psest_1966		Glycine/D-amino acid oxidases (deaminating)	-0.21
11	Psest_0622		Disulfide bond formation protein DsbB	-0.21
12	Psest_3166		Superfamily II DNA and RNA helicases	-0.20
13	Psest_2602		Glycosyltransferases involved in cell wall biogenesis	-0.20
14	Psest_2603		capsular exopolysaccharide family	-0.20
15	Psest_2293		hypothetical protein	-0.20
16	Psest_0597		RND family efflux transporter, MFP subunit	-0.20
17	Psest_1538		Uncharacterized protein conserved in bacteria	-0.19
18	Psest_0393		Methylase of chemotaxis methyl-accepting proteins	-0.19
19	Psest_0583		copper-resistance protein, CopA family	-0.19
20	Psest_3291		Lipid A core - O-antigen ligase and related enzymes	-0.19

Or look for positive cofitness