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  • Negative cofitness for CSW01_15185 from Vibrio cholerae E7946 ATCC 55056

    Cof-type HAD-IIB family hydrolase
    SEED: HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)

    Computing cofitness values with 45 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 CSW01_13615 GGDEF domain-containing protein -0.68
    2 CSW01_04145 transporter -0.61
    3 CSW01_13630 type II secretion protein -0.60
    4 CSW01_00900 hypothetical protein -0.59
    5 CSW01_04915 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -0.58
    6 CSW01_17015 gamma-glutamyltransferase family protein -0.58
    7 CSW01_19325 MltR family transcriptional regulator -0.58
    8 CSW01_07965 LysR family transcriptional regulator -0.58
    9 CSW01_09630 sensor histidine kinase -0.58
    10 CSW01_00945 XRE family transcriptional regulator -0.57
    11 CSW01_05180 tRNA-Asn -0.57
    12 CSW01_02625 inovirus Gp2 family protein -0.57
    13 CSW01_07605 molecular chaperone -0.56
    14 CSW01_08185 hydroxyneurosporene synthase -0.56
    15 CSW01_11860 AMP-dependent synthetase -0.56
    16 CSW01_01830 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -0.56
    17 CSW01_01195 ADP-heptose--LPS heptosyltransferase I -0.56
    18 CSW01_04020 vibriobactin biosynthesis amide synthase VibH -0.55
    19 CSW01_01190 glycosyltransferase family 2 protein -0.55
    20 CSW01_04045 vibriobactin biosynthesis 4'-phosphopantetheinyl transferase VibD -0.55

    Or look for positive cofitness