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  • Negative cofitness for CSW01_06860 from Vibrio cholerae E7946 ATCC 55056

    siroheme synthase
    SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
    KEGG: precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

    Computing cofitness values with 45 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 CSW01_05590 DNA-binding protein VF530 -0.65
    2 CSW01_13695 two-component system response regulator OmpR -0.64
    3 CSW01_02235 hypothetical protein -0.64
    4 CSW01_19275 amino acid ABC transporter ATP-binding protein -0.63
    5 CSW01_00975 peptidase -0.62
    6 CSW01_10390 ferrous iron transport protein A -0.59
    7 CSW01_10180 Na+/H+ antiporter NhaC -0.59
    8 CSW01_10385 Fe(2+) transporter permease subunit FeoB -0.59
    9 CSW01_02720 AraC family transcriptional regulator -0.58
    10 CSW01_13225 phosphoribulokinase -0.58
    11 CSW01_09965 DUF2989 domain-containing protein -0.58
    12 CSW01_09775 lytic murein transglycosylase -0.57
    13 CSW01_10770 methyl-accepting chemotaxis protein -0.57
    14 CSW01_05260 hypothetical protein -0.57
    15 CSW01_01455 peptidase -0.57
    16 CSW01_03190 hypothetical protein -0.57
    17 CSW01_05280 uridine kinase -0.56
    18 CSW01_11760 DUF2850 domain-containing protein -0.56
    19 CSW01_11275 NADPH-dependent ferric siderophore reductase -0.56
    20 CSW01_10360 peptidase M16 -0.56

    Or look for positive cofitness