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  • Negative cofitness for CSW01_04585 from Vibrio cholerae E7946 ATCC 55056

    tRNA 4-thiouridine(8) synthase ThiI
    SEED: tRNA S(4)U 4-thiouridine synthase (former ThiI) / Rhodanese-like domain required for thiamine synthesis
    KEGG: thiamine biosynthesis protein ThiI

    Computing cofitness values with 45 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 CSW01_13810 phosphoenolpyruvate carboxykinase (ATP) -0.75
    2 CSW01_03030 cell division protein ZapE -0.74
    3 CSW01_10630 flagella biosynthesis chaperone FliJ -0.73
    4 CSW01_02155 MSHA pilin protein MshA -0.73
    5 CSW01_02105 MSHA biogenesis protein MshI -0.73
    6 CSW01_01975 chemotaxis protein CheX -0.73
    7 CSW01_10600 flagellar biosynthetic protein FliO -0.72
    8 CSW01_06785 FAA hydrolase family protein -0.72
    9 CSW01_10020 ROK family protein -0.72
    10 CSW01_12365 inorganic phosphate transporter -0.72
    11 CSW01_05730 inosine/guanosine kinase -0.71
    12 CSW01_02205 ribonuclease E/G -0.71
    13 CSW01_06525 cyclic nucleotide-binding protein -0.71
    14 CSW01_10265 c-type cytochrome biogenesis protein CcmF -0.70
    15 CSW01_11920 NupC/NupG family nucleoside CNT transporter -0.70
    16 CSW01_04820 serine hydroxymethyltransferase -0.70
    17 CSW01_03980 IMP dehydrogenase -0.70
    18 CSW01_08850 hypothetical protein -0.69
    19 CSW01_04580 flagellar motor protein MotB -0.69
    20 CSW01_00575 class I SAM-dependent methyltransferase -0.69

    Or look for positive cofitness