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  • Negative cofitness for CSW01_00595 from Vibrio cholerae E7946 ATCC 55056

    heme biosynthesis protein HemY
    SEED: Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)
    KEGG: HemY protein

    Computing cofitness values with 45 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 CSW01_11710 transcriptional regulator -0.74
    2 CSW01_13525 DNA-binding transcriptional regulator CytR -0.74
    3 CSW01_14125 1,4-alpha-glucan branching enzyme -0.73
    4 CSW01_10725 hypothetical protein -0.73
    5 CSW01_01300 sugar ABC transporter -0.73
    6 CSW01_19490 GGDEF domain-containing protein -0.73
    7 CSW01_00900 hypothetical protein -0.71
    8 CSW01_01315 NAD-dependent alcohol dehydrogenase -0.71
    9 CSW01_09145 PTS fructose transporter subunit IIA -0.71
    10 CSW01_13470 transcriptional regulator -0.71
    11 CSW01_01275 phosphomannomutase/phosphoglucomutase -0.71
    12 CSW01_01345 glycosyl transferase family 1 -0.71
    13 CSW01_01295 ABC transporter permease -0.71
    14 CSW01_01285 perosamine synthetase -0.71
    15 CSW01_01310 long-chain fatty acid--CoA ligase -0.71
    16 CSW01_01290 rfbG protein -0.70
    17 CSW01_01280 GDP-mannose 4,6-dehydratase -0.70
    18 CSW01_00215 potassium uptake protein TrkH -0.70
    19 CSW01_04045 vibriobactin biosynthesis 4'-phosphopantetheinyl transferase VibD -0.70
    20 CSW01_01305 acyl carrier protein -0.70

    Or look for positive cofitness