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  • Negative cofitness for CSW01_00335 from Vibrio cholerae E7946 ATCC 55056

    phosphomethylpyrimidine synthase
    SEED: Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17)
    KEGG: thiamine biosynthesis protein ThiC

    Computing cofitness values with 45 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 CSW01_09720 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD -0.65
    2 CSW01_04240 peptidase -0.60
    3 CSW01_13795 type II secretion system protein GspC -0.57
    4 CSW01_18070 FAD-dependent oxidoreductase -0.56
    5 CSW01_18710 hemin ABC transporter substrate-binding protein -0.56
    6 CSW01_14535 RluA family pseudouridine synthase -0.56
    7 CSW01_15350 glycine cleavage system aminomethyltransferase T -0.55
    8 CSW01_16130 acetyltransferase -0.55
    9 CSW01_17835 hypothetical protein -0.54
    10 CSW01_13445 elongation factor P -0.54
    11 CSW01_07025 hypothetical protein -0.53
    12 CSW01_17405 efflux RND transporter periplasmic adaptor subunit -0.51
    13 CSW01_00570 cytochrome c4 -0.51
    14 CSW01_13450 EF-P beta-lysylation protein EpmB -0.50
    15 CSW01_18830 DeoR/GlpR family transcriptional regulator -0.49
    16 CSW01_12665 RDD family protein -0.49
    17 CSW01_09595 peptidylprolyl isomerase -0.48
    18 CSW01_09215 tol-pal system-associated acyl-CoA thioesterase -0.48
    19 CSW01_07300 lipoate--protein ligase -0.48
    20 CSW01_02410 adenine DNA glycosylase -0.48

    Or look for positive cofitness