Negative cofitness for BWI76_RS22705 from Klebsiella michiganensis M5al

siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)

Computing cofitness values with 664 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	BWI76_RS18200		copper homeostasis protein CutC	-0.28
2	BWI76_RS21245		nitrogen regulatory protein P-II	-0.28
3	BWI76_RS06925		iron ABC transporter ATP-binding protein FetA	-0.28
4	BWI76_RS26075		DNA adenine methylase	-0.28
5	BWI76_RS24470		hypothetical protein	-0.27
6	BWI76_RS19035		dTDP-rhamnosyl transferase	-0.27
7	BWI76_RS27250		L-threonine 3-dehydrogenase	-0.26
8	BWI76_RS16745		alpha-acetolactate decarboxylase	-0.26
9	BWI76_RS04200		phosphoglycerate mutase GpmB	-0.25
10	BWI76_RS19040		hypothetical protein	-0.25
11	BWI76_RS11155		penicillin-binding protein activator LpoB	-0.25
12	BWI76_RS27255		2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) (from data)	-0.24
13	BWI76_RS15110		putative excinuclease ABC subunit A	-0.24
14	BWI76_RS19010		polysaccharide pyruvyl transferase yvff	-0.24
15	BWI76_RS08495		cytochrome bd-I ubiquinol oxidase subunit I	-0.24
16	BWI76_RS19765		membrane protein	-0.23
17	BWI76_RS07195		lysine decarboxylase CadA	-0.23
18	BWI76_RS15860		adenine-specific DNA methyltransferase	-0.23
19	BWI76_RS13335		peptidase T	-0.23
20	BWI76_RS00475		sulfurtransferase FdhD	-0.23

Or look for positive cofitness