Negative cofitness for AZOBR_RS14620 from Azospirillum brasilense Sp245

DNA topoisomerase I
SEED: DNA topoisomerase IB (poxvirus type) (EC 5.99.1.2)
KEGG: DNA topoisomerase I

Computing cofitness values with 167 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	AZOBR_RS01345		Fur family transcriptional regulator	-0.37
2	AZOBR_RS08650		cystathionine beta-lyase	-0.35
3	AZOBR_RS01670		imidazole glycerol phosphate synthase	-0.35
4	AZOBR_RS04460		dihydroorotase	-0.35
5	AZOBR_RS13520		dihydroorotate dehydrogenase	-0.35
6	AZOBR_RS01665		imidazoleglycerol-phosphate dehydratase	-0.35
7	AZOBR_RS19500		ATP phosphoribosyltransferase (EC 2.4.2.17) (from data)	-0.35
8	AZOBR_RS03845		Histidinol-phosphatase [alternative form] (EC 3.1.3.15) (from data)	-0.35
9	AZOBR_RS01680		1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data)	-0.34
10	AZOBR_RS01690		phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data)	-0.34
11	AZOBR_RS20575		aspartate carbamoyltransferase	-0.34
12	AZOBR_RS14135		isopropylmalate isomerase	-0.34
13	AZOBR_RS20510		alkyl hydroperoxide reductase subunit C	-0.33
14	AZOBR_RS01490		MucR family transcriptional regulator	-0.33
15	AZOBR_RS32510		sulfoacetaldehyde acetyltransferase	-0.33
16	AZOBR_RS14130		3-isopropylmalate dehydrogenase	-0.33
17	AZOBR_RS01685		imidazole glycerol phosphate synthase	-0.33
18	AZOBR_RS07450		indole-3-glycerol-phosphate synthase	-0.33
19	AZOBR_RS20485		histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data)	-0.33
20	AZOBR_RS12950		chemotaxis protein	-0.32

Or look for positive cofitness