Negative cofitness for Shew_2421 from Shewanella loihica PV-4

diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) (RefSeq)
SEED: diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)

Computing cofitness values with 160 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Shew_2754		diguanylate cyclase (RefSeq)	-0.89
2	Shew_0389		pilus (MSHA type) biogenesis protein MshL (RefSeq)	-0.86
3	Shew_2977		diguanylate cyclase (RefSeq)	-0.85
4	Shew_0391		TPR repeat-containing protein (RefSeq)	-0.85
5	Shew_0386		fimbrial assembly family protein (RefSeq)	-0.84
6	Shew_0392		type II secretion system protein E (RefSeq)	-0.84
7	Shew_3683		extracellular solute-binding protein (RefSeq)	-0.84
8	Shew_0402		MSHA biogenesis protein MshQ (RefSeq)	-0.84
9	Shew_0393		type II secretion system protein (RefSeq)	-0.84
10	Shew_2808		type IV pilus assembly PilZ (RefSeq)	-0.84
11	Shew_0385		biogenesis protein MshI (RefSeq)	-0.83
12	Shew_3380		TatD-related deoxyribonuclease (RefSeq)	-0.82
13	Shew_3381		diguanylate cyclase (RefSeq)	-0.82
14	Shew_0400		methylation site containing protein (RefSeq)	-0.81
15	Shew_3379		hypothetical protein (RefSeq)	-0.80
16	Shew_2988		putative signal transduction protein (RefSeq)	-0.80
17	Shew_0387		MSHA biogenesis protein MshJ (RefSeq)	-0.79
18	Shew_0401		MSHA biogenesis protein MshP (RefSeq)	-0.79
19	Shew_0399		methylation site containing protein (RefSeq)	-0.79
20	Shew_1681		diguanylate cyclase with PAS/PAC sensor (RefSeq)	-0.78

Or look for positive cofitness