Negative cofitness for Shew_2204 from Shewanella loihica PV-4

bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq)
SEED: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
KEGG: phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase

Computing cofitness values with 160 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Shew_3438 type IV-A pilus assembly ATPase PilB (RefSeq) -0.78
2 Shew_3439 type II secretion system protein (RefSeq) -0.75
3 Shew_3759 imidazolonepropionase (RefSeq) -0.70
4 Shew_3436 methylation site containing protein (RefSeq) -0.69
5 Shew_3437 O-antigen polymerase (RefSeq) -0.67
6 Shew_1555 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) -0.66
7 Shew_0470 MATE efflux family protein (RefSeq) -0.65
8 Shew_0653 LuxR family transcriptional regulator (RefSeq) -0.62
9 Shew_3757 urocanate hydratase (RefSeq) -0.62
10 Shew_0231 hypothetical protein (RefSeq) -0.61
11 Shew_3630 bioH protein (RefSeq) -0.61
12 Shew_2407 putative periplasmic protease (RefSeq) -0.60
13 Shew_1625 L-serine dehydratase 1 (RefSeq) -0.60
14 Shew_1809 NAD-glutamate dehydrogenase (RefSeq) -0.60
15 Shew_0225 phosphoheptose isomerase (RefSeq) -0.60
16 Shew_3440 prepilin peptidase (RefSeq) -0.59
17 Shew_1362 sigma-54 dependent trancsriptional regulator (RefSeq) -0.59
18 Shew_0612 hypothetical protein (RefSeq) -0.58
19 Shew_1026 cobalamin biosynthesis protein CbiB (RefSeq) -0.58
20 Shew_0383 malate dehydrogenase (RefSeq) -0.58

Or look for positive cofitness