Negative cofitness for Shew_0553 from Shewanella loihica PV-4

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq)
SEED: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)

Computing cofitness values with 160 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Shew_1776 acetolactate synthase 3 catalytic subunit (RefSeq) -0.52
2 Shew_1441 major facilitator transporter (RefSeq) -0.51
3 Shew_1775 acetolactate synthase 3 regulatory subunit (RefSeq) -0.50
4 Shew_3172 4-aminobutyrate aminotransferase (RefSeq) -0.45
5 Shew_0310 TolC family type I secretion outer membrane protein (RefSeq) -0.43
6 Shew_1540 alcohol dehydrogenase (RefSeq) -0.43
7 Shew_1259 phage transcriptional regulator, AlpA (RefSeq) -0.42
8 Shew_1420 putative hydrolase (RefSeq) -0.42
9 Shew_3173 succinic semialdehyde dehydrogenase (RefSeq) -0.42
10 Shew_0710 metH B12-dependent methionine synthase (RefSeq) -0.42
11 Shew_0312 ABC transporter-related protein (RefSeq) -0.41
12 Shew_2201 hisH imidazole glycerol phosphate synthase subunit HisH (RefSeq) -0.41
13 Shew_1443 integral membrane sensor signal transduction histidine kinase (RefSeq) -0.40
14 Shew_1081 threonine synthase (RefSeq) -0.40
15 Shew_0311 HlyD family type I secretion membrane fusion protein (RefSeq) -0.39
16 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) -0.39
17 Shew_0288 ketol-acid reductoisomerase (RefSeq) -0.39
18 Shew_2553 short-chain dehydrogenase/reductase SDR (RefSeq) -0.39
19 Shew_0388 MSHA biogenesis protein MshK (RefSeq) -0.39
20 Shew_1789 cystathionine beta-lyase (RefSeq) -0.38

Or look for positive cofitness