Negative cofitness for Shew_0416 from Shewanella loihica PV-4

peptidase U62, modulator of DNA gyrase (RefSeq)
SEED: TldE protein, part of TldE/TldD proteolytic complex
KEGG: PmbA protein

Computing cofitness values with 160 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Shew_2569 MerR family transcriptional regulator (RefSeq) -0.60
2 Shew_R0049 tRNA-Pro (RefSeq) -0.60
3 Shew_1247 hypothetical protein (RefSeq) -0.59
4 Shew_3200 multi-sensor hybrid histidine kinase (RefSeq) -0.58
5 Shew_0202 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) -0.58
6 Shew_2753 TPR repeat-containing protein (RefSeq) -0.58
7 Shew_2203 imidazole glycerol phosphate synthase subunit HisF (RefSeq) -0.58
8 Shew_2201 hisH imidazole glycerol phosphate synthase subunit HisH (RefSeq) -0.58
9 Shew_3743 chorismate lyase (RefSeq) -0.58
10 Shew_3173 succinic semialdehyde dehydrogenase (RefSeq) -0.58
11 Shew_0203 acetylglutamate kinase (RefSeq) -0.58
12 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) -0.57
13 Shew_3189 hypothetical protein (RefSeq) -0.57
14 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) -0.57
15 Shew_0287 DNA-binding transcriptional regulator IlvY (RefSeq) -0.57
16 Shew_0293 threonine dehydratase (RefSeq) -0.57
17 Shew_2253 anthranilate phosphoribosyltransferase (RefSeq) -0.57
18 Shew_1081 threonine synthase (RefSeq) -0.57
19 Shew_3478 N-acetylglutamate synthase (RefSeq) -0.57
20 Shew_1031 gltD glutamate synthase subunit beta (RefSeq) -0.57

Or look for positive cofitness