Negative cofitness for Dshi_0446 from Dinoroseobacter shibae DFL-12

putative signal transduction protein with CBS domains (RefSeq)
SEED: CBS domain protein

Computing cofitness values with 196 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Dshi_3088		hypothetical protein (RefSeq)	-0.41
2	Dshi_3968		cation efflux protein (RefSeq)	-0.39
3	Dshi_1713		phosphoribosylformylglycinamidine synthase II (RefSeq)	-0.36
4	Dshi_2728		phosphoribosylamine--glycine ligase (RefSeq)	-0.36
5	Dshi_2798		D-tyrosyl-tRNA(Tyr) deacylase (RefSeq)	-0.36
6	Dshi_2132		amidophosphoribosyltransferase (RefSeq)	-0.35
7	Dshi_1646		inosine-5'-monophosphate dehydrogenase (RefSeq)	-0.34
8	Dshi_1620		protein of unknown function DUF882 (RefSeq)	-0.34
9	Dshi_1888		phosphoribosylglycinamide formyltransferase (RefSeq)	-0.33
10	Dshi_1435		alpha/beta hydrolase fold (RefSeq)	-0.33
11	Dshi_1889		phosphoribosylformylglycinamidine cyclo-ligase (RefSeq)	-0.32
12	Dshi_0615		orotidine 5'-phosphate decarboxylase (RefSeq)	-0.32
13	Dshi_0821		Glycine hydroxymethyltransferase (RefSeq)	-0.32
14	Dshi_4159		Alcohol dehydrogenase GroES domain protein (RefSeq)	-0.32
15	Dshi_1359		protein of unknown function DUF35 (RefSeq)	-0.32
16	Dshi_0653		Prephenate dehydratase (RefSeq)	-0.31
17	Dshi_2372		orotate phosphoribosyltransferase (RefSeq)	-0.31
18	Dshi_2758		transcriptional regulator, GntR family (RefSeq)	-0.31
19	Dshi_0790		hypothetical protein (RefSeq)	-0.31
20	Dshi_0958		TRAP dicarboxylate transporter, DctP subunit (RefSeq)	-0.31

Or look for positive cofitness