Negative cofitness for Rru_A3377 from Rhodospirillum rubrum S1H

Alpha/beta hydrolase fold (NCBI)
SEED: 2-hydroxymuconic semialdehyde hydrolase (EC 3.1.1.-)

Computing cofitness values with 60 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rru_A0352		RepA (NCBI)	-0.68
2	Rru_A0188		ABC transporter, transmembrane region (NCBI)	-0.62
3	Rru_A0094		Binding-protein-dependent transport systems inner membrane component (NCBI)	-0.61
4	Rru_A0843		ABC transporter component (NCBI)	-0.52
5	Rru_A1131		Aminotransferase, class IV (NCBI)	-0.52
6	Rru_A0350		Helix-turn-helix protein, CopG (NCBI)	-0.51
7	Rru_A0810		hypothetical protein (NCBI)	-0.50
8	Rru_A3682		Cytochrome B561 (NCBI)	-0.50
9	Rru_A1512		ISSo9, nucleotidyltransferase domain protein (NCBI)	-0.50
10	Rru_A1906		Sulfate transporter/antisigma-factor antagonist (NCBI)	-0.50
11	Rru_A3024		Prolyl 4-hydroxylase, alpha subunit (NCBI)	-0.49
12	Rru_A3686		Alanine dehydrogenase and pyridine nucleotide transhydrogenase (NCBI)	-0.48
13	Rru_A2610		hypothetical protein (NCBI)	-0.48
14	Rru_A3726		inner-membrane translocator (NCBI)	-0.48
15	Rru_A2473		PAS/PAC Sensor Signal Transduction Histidine Kinase (NCBI)	-0.48
16	Rru_A2143		methyltransferase (NCBI)	-0.48
17	Rru_A1937		hypothetical protein (NCBI)	-0.47
18	Rru_A3314		Uncharacterized phage-encoded protein-like (NCBI)	-0.46
19	Rru_A1424		NADH dehydrogenase (ubiquinone), 30 kDa subunit (NCBI)	-0.46
20	Rru_A1415		Protein of unknown function DUF132 (NCBI)	-0.46

Or look for positive cofitness