Conservation of cofitness between b1971 and b3510 in Escherichia coli BW25113

12 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b1971	yedY	hypothetical protein (NCBI)	1.0	b3510	hdeA	acid-resistance protein, possible chaperone , subunit of HdeA dimer, inactive form of acid-resistance protein (Katherine Huang)	0.15	11
Escherichia coli ECRC98	0.99	JDDGAC_00140	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	JDDGAC_19935	hdeA	acid-activated periplasmic chaperone HdeA	—	—
Escherichia coli ECRC99	0.99	KEDOAH_02540	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	KEDOAH_11840	hdeA	acid-activated periplasmic chaperone HdeA	—	—
Escherichia coli ECRC102	0.99	NIAGMN_02500	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	NIAGMN_14070	hdeA	acid-activated periplasmic chaperone HdeA	—	—
Escherichia coli ECRC101	0.99	MCAODC_19840	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	MCAODC_06820	hdeA	acid-activated periplasmic chaperone HdeA	—	—
Escherichia coli ECRC101	0.99	OKFHMN_25555	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	OKFHMN_16305	hdeA	acid-activated periplasmic chaperone HdeA	—	—
Escherichia coli BL21	0.99	ECD_01886		membrane-anchored, periplasmic TMAO, DMSO reductase	1.00	ECD_03358		stress response protein acid-resistance protein	low	> 60
Escherichia coli Nissle 1917	0.98	ECOLIN_RS11200		protein-methionine-sulfoxide reductase catalytic subunit MsrP	0.99	ECOLIN_RS20080		acid-activated periplasmic chaperone HdeA	—	—
Escherichia fergusonii Becca	0.98	EFB2_01979		Protein-methionine-sulfoxide reductase catalytic subunit MsrP	0.99	EFB2_00299		Acid stress chaperone HdeA	low	> 86
Escherichia coli ECOR38	0.98	HEPCGN_03915	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	0.99	HEPCGN_15205	hdeA	acid-activated periplasmic chaperone HdeA	—	—
Escherichia coli ECOR27	0.98	NOLOHH_16185	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	NOLOHH_08270	hdeA	acid-activated periplasmic chaperone HdeA	low	> 57
Escherichia coli HS(pFamp)R (ATCC 700891)	0.98	OHPLBJKB_01758		Protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	OHPLBJKB_00193		Acid stress chaperone HdeA	low	> 73
Escherichia coli ECRC62	0.93	BNILDI_14975	msrP	protein-methionine-sulfoxide reductase catalytic subunit MsrP	1.00	BNILDI_03285	hdeA	acid-activated periplasmic chaperone HdeA	—	—

Not shown: 62 genomes with orthologs for b1971 only; 0 genomes with orthologs for b3510 only