Top cofit genes for SMc01053 from Sinorhizobium meliloti 1021

siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	SMc02124		nitrite reductase	1.00	0.99
2	SMc00092		phosphoadenosine phosphosulfate reductase	0.97	0.98
3	SMc00090		sulfate adenylyltransferase	0.90	0.97
4	SMc00091		sulfate adenylyltransferase	0.97	0.97
5	SMc02123		required for sulfate utilization, putative electron transport protein for sulfite reductase (from data)	0.92	0.96
6	SMc03823		isopropylmalate isomerase large subunit	1.00	0.96
7	SMc01054		required for sulfate utilization, putative electron source for sulfite reductase CysI (from data)	0.93	0.96
8	SMc01843		5,10-methylenetetrahydrofolate reductase	0.99	0.96
9	SMc03797		homoserine O-succinyltransferase	0.94	0.96
10	SMc03112		B12-dependent methionine synthase	0.90	0.96
11	SMc02217		O-succinylhomoserine sulfhydrylase	0.96	0.96
12	SMc02899		prephenate dehydratase	0.93	0.95
13	SMc04405		3-isopropylmalate dehydrogenase	0.99	0.95
14	SMc02717		2-isopropylmalate synthase	0.94	0.95
15	SMc04045		dihydroxy-acid dehydratase	1.00	0.95
16	SMc01494		phosphoserine phosphatase	0.73	0.95
17	SMc00488		phosphoribosylformylglycinamidine synthase II	0.89	0.95
18	SMc00640		phosphoserine aminotransferase	0.77	0.94
19	SMc00993		phosphoribosylamine--glycine ligase	0.86	0.94
20	SMc01726		acetylglutamate kinase	1.00	0.94

Or look for negative cofitness