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Gene
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Cofit
Protein
Homologs
Top cofit genes for Rv3872 from
Mycobacterium tuberculosis H37Rv
PE family-related protein PE35
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv2725c
Probable GTP-binding protein HflX
no
0.31
2
Rv1988
Probable 23S rRNA methyltransferase Erm(37)
no
0.29
3
Rv1915
Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl)
no
0.24
4
Rv1909c
Ferric uptake regulation protein FurA (fur)
no
0.23
5
Rv2372c
Conserved hypothetical protein
no
0.23
6
Rv1491c
Conserved membrane protein
no
0.23
7
Rv2124c
5-methyltetrahydrofolate--homocystein methyltransferase MetH (methionine synthase, vitamin-B12 dependent isozyme) (ms)
no
0.23
8
Rv1739c
Probable sulphate-transport transmembrane protein ABC transporter
no
0.22
9
Rv1597
Hypothetical protein
no
0.22
10
Rv1691
Conserved hypothetical protein
no
0.22
11
Rv2823c
Conserved protein
no
0.22
12
Rv0522
Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease)
no
0.22
13
Rv3236c
Probable conserved integral membrane transport protein
no
0.22
14
Rv2236c
Probable cobalamin biosynthesis transmembrane protein CobD
no
0.21
15
Rv1100
Conserved protein
no
0.21
16
Rv1683
Possible bifunctional enzyme; long-chain acyl-CoA synthase and lipase.
no
0.21
17
Rv0758
Possible two component system response sensor kinase membrane associated PhoR
no
0.21
18
Rv2510c
Conserved protein
no
0.21
19
Rv3077
Possible hydrolase
no
0.21
20
Rv1762c
Unknown protein
no
0.21
Or look for
negative cofitness