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Cofit
Protein
Homologs
Top cofit genes for Rv3813c from
Mycobacterium tuberculosis H37Rv
Conserved protein
SEED: Cof family hydrolase
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0888
Probable exported protein
no
0.41
2
Rv1062
Conserved hypothetical protein
no
0.39
3
Rv1387
PPE family protein PPE20
no
0.36
4
Rv3190A
Conserved protein
no
0.36
5
Rv0090
Possible membrane protein
no
0.35
6
Rv2659c
Probable PhiRv2 prophage integrase
no
0.35
7
Rv3167c
Probable transcriptional regulatory protein (probably TetR-family)
no
0.35
8
Rv0413
Possible mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase)
no
0.33
9
Rv1593c
Conserved protein
no
0.32
10
Rv1781c
Probable 4-alpha-glucanotransferase MalQ (amylomaltase) (disproportionating enzyme) (D-enzyme)
no
0.32
11
Rv1205
Conserved hypothetical protein
0.17
0.32
12
Rv1100
Conserved protein
no
0.32
13
Rv2296
Probable haloalkane dehalogenase
no
0.31
14
Rv3339c
Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)
0.58
0.31
15
Rv2704
Conserved protein
no
0.31
16
Rv3880c
ESX-1 secretion-associated protein EspL
no
0.30
17
Rv0823c
Possible transcriptional regulatory protein
no
0.30
18
Rv1367c
Conserved protein
no
0.30
19
Rv3881c
Secreted ESX-1 substrate protein B, EspB. Conserved alanine and glycine rich protein
no
0.30
20
Rv0648
Alpha-mannosidase
no
0.30
Or look for
negative cofitness