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  • Top cofit genes for Rv3687c from Mycobacterium tuberculosis H37Rv

    Anti-anti-sigma factor RsfB (anti-sigma factor antagonist) (regulator of sigma F B)
    SEED: Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv2265 Possible conserved integral membrane protein no 0.33
    2 Rv0449c Conserved hypothetical protein no 0.31
    3 Rv1758 Probable cutinase Cut1 no 0.30
    4 Rv2634c PE-PGRS family protein PE_PGRS46 no 0.29
    5 Rv3313c Probable adenosine deaminase Add (adenosine aminohydrolase) no 0.29
    6 Rv2098c PE-PGRS family protein PE_PGRS36 no 0.29
    7 Rv2624c Universal stress protein family protein no 0.27
    8 Rv3303c NAD(P)H quinone reductase LpdA no 0.27
    9 Rv0195 Possible two component transcriptional regulatory protein (probably LuxR-family) no 0.27
    10 Rv2099c PE family protein PE21 no 0.26
    11 Rv1114 Possible toxin VapC32. Contains PIN domain. no 0.26
    12 Rv1154c Hypothetical protein no 0.26
    13 Rv3445c ESAT-6 like protein EsxU no 0.25
    14 Rv2301 Probable cutinase Cut2 no 0.25
    15 Rv1137c Hypothetical protein no 0.25
    16 Rv2365c Conserved hypothetical protein no 0.25
    17 Rv1886c Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular alpha-antigen) no 0.25
    18 Rv0798c 29 KDa antigen CFP29 no 0.25
    19 Rv2655c Possible PhiRv2 prophage protein no 0.25
    20 Rv2107 PE family protein PE22 no 0.25

    Or look for negative cofitness