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Cofit
Protein
Homologs
Top cofit genes for Rv3683 from
Mycobacterium tuberculosis H37Rv
Conserved protein
SEED: putative secreted protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0092
Cation transporter P-type ATPase a CtpA
no
0.43
2
Rv0190
Conserved protein
no
0.43
3
Rv1640c
Lysyl-tRNA synthetase 2 LysX
no
0.40
4
Rv0353
Probable heat shock protein transcriptional repressor HspR (MerR family)
no
0.40
5
Rv2709
Probable conserved transmembrane protein
no
0.39
6
Rv0475
Iron-regulated heparin binding hemagglutinin HbhA (adhesin)
no
0.38
7
Rv0158
Probable transcriptional regulatory protein (possibly TetR-family)
no
0.38
8
Rv0758
Possible two component system response sensor kinase membrane associated PhoR
no
0.36
9
Rv2781c
Possible alanine rich oxidoreductase
0.24
0.36
10
Rv1798
ESX conserved component EccA5. ESX-5 type VII secretion system protein.
no
0.36
11
Rv1791
PE family protein PE19
no
0.35
12
Rv2468c
Conserved protein
no
0.33
13
Rv2427c
Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)
no
0.33
14
Rv1956
Possible antitoxin HigA
no
0.32
15
Rv2862c
Conserved hypothetical protein
no
0.32
16
Rv3136A
Conserved protein
no
0.32
17
Rv2181
Alpha(1->2)mannosyltransferase
no
0.32
18
Rv1957
Hypothetical protein
no
0.32
19
Rv3649
Probable helicase
no
0.32
20
Rv0047c
Conserved protein
no
0.32
Or look for
negative cofitness