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Cofit
Protein
Homologs
Top cofit genes for Rv3650 from
Mycobacterium tuberculosis H37Rv
PE family protein PE33
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0653c
Possible transcriptional regulatory protein (probably TetR-family)
no
0.40
2
Rv1336
Cysteine synthase B CysM (CSASE B) (O-phosphoserine sulfhydrylase B) (O-phosphoserine (thiol)-lyase B)
no
0.40
3
Rv1850
Urease alpha subunit UreC (urea amidohydrolase)
no
0.38
4
Rv3412
Conserved hypothetical protein
no
0.36
5
Rv3194c
Possible conserved secreted protein
no
0.35
6
Rv2216
Conserved protein
no
0.35
7
Rv0251c
Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A)
no
0.34
8
Rv0989c
Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase)
no
0.34
9
Rv1187
Probable pyrroline-5-carboxylate dehydrogenase RocA
no
0.33
10
Rv1058
Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.32
11
Rv2588c
Probable conserved membrane protein secretion factor YajC
no
0.31
12
Rv0470c
Mycolic acid synthase PcaA (cyclopropane synthase)
no
0.31
13
Rv0655
Possible ribonucleotide-transport ATP-binding protein ABC transporter Mkl
no
0.30
14
Rv3494c
Mce-family protein Mce4F
no
0.30
15
Rv3496c
Mce-family protein Mce4D
no
0.30
16
Rv2799
Probable membrane protein
no
0.30
17
Rv1287
Conserved hypothetical protein
no
0.29
18
Rv1334
Possible hydrolase
no
0.29
19
Rv0200
Possible conserved transmembrane protein
no
0.29
20
Rv1637c
Conserved protein
no
0.29
Or look for
negative cofitness