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  • Top cofit genes for Rv3540c from Mycobacterium tuberculosis H37Rv

    Probable lipid transfer protein or keto acyl-CoA thiolase Ltp2
    SEED: Lipid carrier protein IgrF

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv3543c Probable acyl-CoA dehydrogenase FadE29 no 0.36
    2 Rv1356c Hypothetical protein no 0.32
    3 Rv3537 Probable dehydrogenase no 0.31
    4 Rv3553 Possible oxidoreductase no 0.30
    5 Rv0761c Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB no 0.29
    6 Rv0692 Conserved hypothetical protein no 0.28
    7 Rv3812 PE-PGRS family protein PE_PGRS62 no 0.28
    8 Rv0922 Possible transposase no 0.28
    9 Rv3544c Probable acyl-CoA dehydrogenase FadE28 no 0.28
    10 Rv1106c 3-beta-hydroxysteroid dehydrogenase no 0.27
    11 Rv3821 Probable conserved integral membrane protein no 0.27
    12 Rv3545c Probable cytochrome P450 125 Cyp125 no 0.27
    13 Rv0551c Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) no 0.27
    14 Rv2070c Precorrin-6X reductase CobK no 0.27
    15 Rv0895 Possible triacylglycerol synthase (diacylglycerol acyltransferase) no 0.26
    16 Rv1188 Probable proline dehydrogenase no 0.26
    17 Rv3571 Reductase component of 3-ketosteroid-9-alpha-hydroxylase KshB no 0.25
    18 Rv2340c PE-PGRS family protein PE_PGRS39 no 0.25
    19 Rv0648 Alpha-mannosidase no 0.25
    20 Rv1179c Unknown protein no 0.25

    Or look for negative cofitness