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  • Top cofit genes for Rv3485c from Mycobacterium tuberculosis H37Rv

    Probable short-chain type dehydrogenase/reductase
    SEED: Short-chain dehydrogenase/reductase SDR

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv0552 Conserved protein no 0.28
    2 Rv0642c Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) no 0.27
    3 Rv0445c Alternative RNA polymerase sigma factor SigK no 0.26
    4 Rv0419 Possible lipoprotein peptidase LpqM no 0.25
    5 Rv1585c Possible phage PhiRv1 protein no 0.25
    6 Rv1834 Probable hydrolase no 0.24
    7 Rv0493c Conserved protein no 0.24
    8 Rv1141c Probable enoyl-CoA hydratase EchA11 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) no 0.24
    9 Rv0931c Transmembrane serine/threonine-protein kinase D PknD (protein kinase D) (STPK D) no 0.23
    10 Rv2513 Hypothetical protein no 0.23
    11 Rv2408 Possible PE family-related protein PE24 no 0.23
    12 Rv3706c Conserved hypothetical proline rich protein no 0.23
    13 Rv0874c Conserved hypothetical protein no 0.23
    14 Rv3277 Probable conserved transmembrane protein no 0.23
    15 Rv0851c Probable short-chain type dehydrogenase/reductase no 0.23
    16 Rv3406 Probable dioxygenase no 0.22
    17 Rv0485 Possible transcriptional regulatory protein no 0.22
    18 Rv3497c Mce-family protein Mce4C no 0.22
    19 Rv0691c Probable transcriptional regulatory protein no 0.22
    20 Rv1114 Possible toxin VapC32. Contains PIN domain. no 0.22

    Or look for negative cofitness