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Cofit
Protein
Homologs
Top cofit genes for Rv3477 from
Mycobacterium tuberculosis H37Rv
PE family protein PE31
SEED: PE family protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv3478
PE family protein PPE60
no
0.39
2
Rv1234
Probable transmembrane protein
no
0.33
3
Rv0043c
Probable transcriptional regulatory protein (probably GntR-family)
no
0.32
4
Rv3887c
ESX conserved component EccD2. ESX-2 type VII secretion system protein. Probable transmembrane protein.
no
0.32
5
Rv1798
ESX conserved component EccA5. ESX-5 type VII secretion system protein.
no
0.31
6
Rv2351c
Membrane-associated phospholipase C 1 PlcA (MTP40 antigen)
no
0.31
7
Rv0983
Probable serine protease PepD (serine proteinase) (MTB32B)
no
0.30
8
Rv0012
Probable conserved membrane protein
no
0.29
9
Rv3122
Hypothetical protein
no
0.28
10
Rv3586
Conserved hypothetical protein
no
0.28
11
Rv1824
Conserved hypothetical membrane protein
no
0.27
12
Rv3319
Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase)
no
0.27
13
Rv1823
Conserved protein
no
0.27
14
Rv0092
Cation transporter P-type ATPase a CtpA
no
0.27
15
Rv2752c
Conserved hypothetical protein
no
0.27
16
Rv1638
Probable excinuclease ABC (subunit A-DNA-binding ATPase) UvrA
no
0.27
17
Rv2901c
Conserved protein
no
0.27
18
Rv0758
Possible two component system response sensor kinase membrane associated PhoR
no
0.26
19
Rv3803c
Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C)
no
0.25
20
Rv2091c
Probable membrane protein
no
0.25
Or look for
negative cofitness