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Cofit
Protein
Homologs
Top cofit genes for Rv3131 from
Mycobacterium tuberculosis H37Rv
Conserved protein
SEED: Possible membrane protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0450c
Probable conserved transmembrane transport protein MmpL4
no
0.33
2
Rv2284
Probable esterase LipM
no
0.33
3
Rv1469
Probable cation transporter P-type ATPase D CtpD
no
0.32
4
Rv0146
Possible S-adenosylmethionine-dependent methyltransferase
no
0.32
5
Rv0032
Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase)
no
0.31
6
Rv1164
Probable respiratory nitrate reductase (gamma chain) NarI
no
0.30
7
Rv1872c
Possible L-lactate dehydrogenase (cytochrome) LldD2
no
0.30
8
Rv3192
Conserved hypothetical alanine and proline-rich protein
no
0.30
9
Rv0693
Probable coenzyme PQQ synthesis protein E PqqE (coenzyme PQQ synthesis protein III)
no
0.29
10
Rv2831
Probable enoyl-CoA hydratase EchA16 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase)
no
0.29
11
Rv2796c
Probable conserved lipoprotein LppV
no
0.29
12
Rv1645c
Conserved hypothetical protein
no
0.29
13
Rv2646
Probable integrase
no
0.28
14
Rv1978
Conserved protein
no
0.28
15
Rv1608c
Probable peroxidoxin BcpB
no
0.28
16
Rv0274
Conserved protein
no
0.28
17
Rv2953
Enoyl reductase
no
0.27
18
Rv3354
Conserved hypothetical protein
no
0.26
19
Rv2072c
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating) CobL
no
0.26
20
Rv1519
Conserved hypothetical protein
no
0.26
Or look for
negative cofitness